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Neuropathy

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Signs and Symptoms

Symptoms depend on the type of nerve(s) affected (e.g., motor, sensory, autonomic) and where the nerve is located in the body. One or more types of nerve may be damaged.

Muscle weakness, cramps, and spasms are associated with motor nerve damage. In some cases, there may be loss of balance and coordination.

Sensory nerve damage can produce tingling, numbness, and pain. Pain associated with sensory nerve damage is variously described as:

  • Sensation of wearing an invisible "glove" or "sock"
  • Burning, freezing, or electric-like
  • Extreme sensitivity to touch

If the autonomic nerves are damaged, involuntary functions may be affected. Symptoms that can result from this type of damage include abnormal blood pressure and heart rate, reduced ability to perspire, constipation, bladder dysfunction (e.g., incontinence), and sexual dysfunction.

Some neuropathies develop suddenly; others progress slowly, even over a number of years. Severity varies among individuals and may vary in the same individual throughout the day. Symptoms generally are more severe at night.


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  • Physician-developed and -monitored.
    Original Date of Publication: 01 Jan 2000
    Reviewed by: Sandeep K. Aggarwal, M.D., Stanley J. Swierzewski, III, M.D.
    Last Reviewed: 23 Jul 2007

    Neuropathy, Neuropathy Signs and Symptoms reprinted with permission from neurologychannel.com
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    This page last modified: 31 Mar 2009

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