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Cluster Headache Prevention

Prednisilone (Prednisone)
This is a steroid medication that is taken initially in high doses, then tapered over days to weeks, depending on the response. This medication is best if used for short periods of time, as long term steroid use is associated with many complications.

Lithium carbonate
This medication is taken orally, usually twice a day in order to interrupt the cluster. Laboratory testing including lithium levels should be followed closely. Side effects include tremor, increased thirst and gastrointestinal symptoms.

Verapamil
This is a medication that can also be effective in migraine. It can be taken twice daily in a sustained oral preparation. Side effects include dizziness and constipation.


  • « Cluster Headache Treatment

  • Physician-developed and -monitored.
    Original Date of Publication: 02 Jan 2002
    Reviewed by: Stanley J. Swierzewski, III, M.D.
    Last Reviewed: 01 Dec 2007

    Headache, Cluster Headache Prevention reprinted with permission from neurologychannel.com
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    This page last modified: 12 Mar 2009

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