Feline Infectious Peritonitis

[Marnixowner]

I believe Atabrin / Atabrine is available in the U.K. under the name Mepacrine. i think it is still used to treat skin conditions so it may well be available with a prescription. If you do decide to use this drug please report back if it has a positive result.

[jnz]

"Basically a small cytokine immune response storm. Small that is, but enough to kick it into gear. The drug has the capability to penetrate the virus and creates a T response to destroy it. Now this virus does not cause the immune response to destroy its own good cells." Thank you, this is what I needed.

[Kirbyman]

[quote="Daveyo"]Hmmm just thought of something. Perhaps you can help this person and get some made and send it to them if they cannot find someone to make it. You can use a bit of ingenuity to get it delivered.[/quote]

Are you talking about Atabrine here, or serum?
And how much would that cost?

[jnz]

I hope to have a price for Atabrine within the next few days. Since it is not commercially available and has to be made on an as-needed basis, you can bet it won't be cheap.

[Daveyo]

I am talking about Atabrine. How much I don't know cost wise today and it varies. Perhaps jnz can give you a ballpark figure. Serum is a different proceedure requiring somebody having the right equipment to make it possible plus the """"GOOD CAT"""" that meets all the requirements. This same cat has to be really of good mixed breed. The more it is mixed in breed the better the serum. So keep that in mind. The same applies to dogs as well.

Dr. Sears and I have found if we get a dog with a good history of mixed breeding with various dogs on the genetic scale, the serum is fantastic. The same for cats. Problem is finding one that is certified really mixed on the breeding side. Many will say this and that so be careful here. You need to find such that is really true and certified really mixed. Now once you do get this particular animal and it also meets the other requirements, Ok now you get the serum. You can only get so much from this animal and after that no more from that animal. That little bit of serum is all you got and that is the only known holy grail to cure the diseases.

This applies only for the animals body and not for the central nervous system. We have not yet tried to test the serum in the central nervous system. Why many of you might ask me. The reason is the Serum is ANTIBODIES!!!!! For the central nervous system we have tried the vaccine and it works and there is no serious after effects from the vaccine in the cerebral fluids. Vaccine does not contain antibodies. This is the big difference.

Putting antibodies into a otherwise clean system of cerebral fluids might cause what?????? even though the victim has the virus inside the cerebral fluids. We don't know. The Mayo Clinic is now making such attempt on HUMANS involving Multiple Sclerosis. None has been tried on the animal yet to see its results.

I know myself of what is involved here. Sooner or later I probably will have to force myself to give it a shot on some animal. The question is when. Well I have decided to wait and see what the Mayo Clinic results are and see if any humans died from such attempt or what kind of complications came from such attempt. They have talked to me and an argument ensued and I told them where to go. It remains to be seen and this is all entirely a new scenario. It can go either way.

The danger is the immune response and the T response inside the cerebral fluids. I already know the cytokine storm created by the vaccine and of what it does both ways body and cerebral. It was a success. I also know what the serum does regarding its cytokine storm on the body and it also was a success. The cerebral fluid and serum (antibodies) ?????? unknown at this time.

If you want my opinion > well it is known that the cerebral fluids do contain antibodies to protect the barrier. It is also known that there is scouts (laymans terms) that patrol the fluid constantly 24/7 around the clock. When it finds an intruder present it sends a signal to the auto-immune system in the brain area. From there this system then triggers a T response and sends out its soldiers to respond and attack the intruder. In a sense it does have antibodies. So it stands to reason that the cerebral fluid does have a protection layer in the cerebral fluid but what kind????? That we don't know. Now if we inject antibodies into the cerebral fluid, what response will the scouts tell the auto-immune system that is inside the fluid????? Will it ask for an attack or leave it alone???? If it asks for an attack, the animal or human will die. Because it will create a deadly immune response and it will destroy everything in the cerebral fluid. The key is those T cells. Now I already discovered on how to control those T cells itself with a virus present in the cerebral fluid. I don't know if I can also control the T cells with antibodies present. Big difference here. But I will bet you if I proceed to continue to experiment with what knowledge I have I will also obtain the answer to the antibody question as well.

The Mayo clinic is aware of what I have done, but we have a big argument between us. So I therefore stepped aside and not tell them how it is done. They are on their own. Also the smarts have mistreated me and Dr. Sears a lot and I will remember this as well. To the demise of animals and humans alike who truly need me. I am sorry but I want to be PAID and I mean PAID for my discovery and it is not going to be free either.

So, what does my discovery mean to the world??? It means everything, it means I have opened up the door to many possibilities to curing people of various afflictions and refreshes the dried up well for drugs and vaccines that can be made and solves many riddles involving the auto-immune system and how to control a very important deadly cell that always causes so many problems to the vaccines and drugs, and we both have figured out a way to make RAPID CURES which is an achievement itself because no one has ever come up with a way to cure an animal or human with a speed that Dr. Sears and I have created. We are talking of a speed in HOURS and not in days or weeks.

This is what the smarts are telling us. We are doing voodoo medicine which by their laws goes against everything they know and they claim it being impossible yet we keep getting excellent results and proof, and the animals are getting cured left and right with no end in sight. go figure. What Dr. Sears and I have done is altered the lab and medical protocol which defies their reasoning. Now for this to be in the books will take months and possibly years, and a ton of money to spend, and in the meantime people and animals are dying left and right. Something needs to be done to accelerate this delay and help those in need. We are fighting for you but how to do with a limited income source to battle the Giants who have millions of bucks and control the information to many doctors and researchers worldwide.??????

A schism is in effect here.

End of story

Daveyo

[Marnixowner]

I just want to check that the 50mg dose is correct.Information I have found on this drug for the treatment of giardiasis states a pediatric dose of 2mg per kg of body weight 3 times a day. I understand that the dosing recommendations I've found are not for this disease but the kitten I wish to dose only weighs just over 2kg. That would be 12mg a day. Is such a heavy dose safe on such a small animal? Sorry to keep on but this drug is only available through prescription so I will need to convince my vet that this medication safe and a credable treatment for FIP in order to get him to write a prescription. I presume the vet has to follow certain guidelines on whether something that has not gone through clinical trials can be prescribed to an animal. Any further information you have on this treatment would be appreciated.

[Kirbyman]

Marnixowner, is it the wet or dry form of FIP?
I have had contact with Daveyo, and apparently Atabrine is only usefull for the dry form.
For the wet form you would need Quinine, US brandnames are Qualaquin, Quinamm and Quiphile.

Check freedom-pharmacy online for the second, it should be available without prescription,
but I would still advise consulting your vet beforehand. It's around 70 USD for 100 tablets of 200 mg.
You could then get your pharmacy to break it down into the needed smaller dosage.
But, as of yet, I don't have any dosing information on the use of it.
Still awaiting Daveyo to reply.

Kirbyman, who hopes your little friend can pull through.
I have started INTERFERON treatment Friday, and unfortunately it doesn't catch on.
I fear I may have to put Kirby down this evening.

I have not been able to localize Quinine here in Belgium.
And fear at this point anything would be too late.
He can only eat a bit of whipped cream anymore,
he has to vomit, when I try to forcefeed the food the vet gave.
And can't chew anymore, he strecks out his neck, when he tries to open up his mouth,
but his mouth won't open. He can lick (a little bit) of cream only.
I wonder if this unability to open his mouth to grab something is the FIP,
or a negative side-effect of the interferon or prednisolone?

I should add that my little friend had less chance, to begin with,
because he also has cerebellar hypoplasia, which is underdeveloped lower brain,
causing severe balancing problems, he can hardly walk,
but he had this since he was born, and got used to that, and played regardless
with his brother and sister, but much slower and falling down a lot, of course.
Now, the quality of his life is heartbraking, he can just sit in the couch,
hardly get up to get to the litter box and like I said, he can't really eat anymore,
the vet is coming over this evening, and unless she thinks Kirby still has a fighting chance,
which, unfortunately, I doubt, I will ask to put him down, but with the slow method,
which will make him fall asleep first, and then he will sleep deeper and deeper,
and eventually die in his sleep, this could take up to half an hour,
but he will not have to be scared, like with the other method,
a lethal injection into heart or kidney.
(Since kidney and liver are affected by FIP, it may not even work properly.)

[Marnixowner]

I am very sorry to hear about the illness of you cat. I understand how it feels to watch your most special friend as they are overcome by this dreadful disease. Marnix has dry form FIP so it was very hard to diagnose in the first place. The first vet we went to told us that he had 'just gone blind' and probably would never recover his sight but apart from that nothing else was wrong with him. As you can imagine we weren't particually satisfied with this diagnosis so we phoned around to find a vet who had more experience with feline eye problems. They were able to diagnose the FIP. They have prescribed him with prednisolone which has partially restored his sight and made him a lot more confidant but now he is starting to lose his appetite and is losing his strength.Atabrine is available in the Uk under the name Mepacrine by prescription only. I'm hoping my vet will write the prescription but I think they may be reluctant to prescribe anything that has not undergone clinical trials. I hope I can source these drugs while there is still time. It is so frustrating when it is this difficult to take steps toward what little hope there is left. My thoughts are with you.

[Kirbyman]

Thank you for your sympathy and I wish your cat Marnix the best!

[Daveyo]

The dose that I have posted here is for your animal. It is required if you want any results. 50mg is rather small and it is not high at all.

Daveyo

Sometime VETS even prescribe 500 mg doses like antibiotics. Even for a human for me that is high and good because it is strong. They even have aspirins that high too.

Now when you say give 50mg of phenobarbital to an animal that is high because the drug itself is very strong even in a small dose and its also very addictive. This is given to animals having seizures resulting from Canine Distemper. Normal dose for small dogs is like anywhere from 8 mg to 20 mg every 12-24 hours. Long term effects have to be carefully watched. As time goes on the immune system begins to resist the drug requiring a higher dose to overcome it. That is the danger even to humans as well when taking drugs and have no real reason of needing it. When the real McCoy time takes place and you need that drug, your out of luck because your system has built a huge resistance base against it.